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ChemicalBook CAS DataBase List 90596-75-1

90596-75-1 Structure

90596-75-1

Name	YT 146
CAS	90596-75-1
MDL Number	MFCD00905325
MOL File	90596-75-1.mol

Synonyms

YT 146 YT146|||YT-146 2-(1-Octynyl)adenosine

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Hazard Information

Uses

YT 146 is a potent agonist of A2 adenosine receptor (A2 AR) agonist. YT 146 causes a concentreation dependent cAMP accumulation, with the EC50 of 1.5 nM. YT 146 has cardioprotective effects[1].

IC 50

A2AR

References

[1] Jun Sasamori, et al. Cardioprotective effects of 2-octynyladenosine (YT-146) in ischemic/reperfused rat hearts. J Cardiovasc Pharmacol. 2011 Feb;57(2):166-73. DOI:10.1097/FJC.0b013e318201c264

Spectrum Detail

YT 146(90596-75-1)¹HNMR

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