ChemicalBook CAS DataBase List 9038-95-3

9038-95-3

Name	POLY(ETHYLENE GLYCOL-CO-PROPYLENE GLYCOL) MONOBUTYL ETHER
CAS	9038-95-3
EINECS(EC#)	231-545-4
Molecular Formula	CH3(CH2)3(OCH2CH2)x[OCH2CH(CH3)]yOH
MDL Number	MFCD00198079
Molecular Weight	176.26
MOL File	9038-95-3.mol

Chemical Properties

Appearance	liquid
Boiling point	>200 °C(lit.)
density	1.056 g/mL at 25 °C
refractive index	n20/D 1.46
Fp	>230 °F
solubility	H₂O: at <40 °Csoluble
Stability:	Stable. Incompatible with strong acids, strong bases, strong oxidizing agents.
InChI	InChI=1S/C4H10O.C3H6O.C2H4O/c1-2-3-4-5;1-3-2-4-3;1-2-3-1/h5H,2-4H2,1H3;3H,2H2,1H3;1-2H2
InChIKey	YTJMOZGBQLKJKS-UHFFFAOYSA-N
SMILES	C(CO)CC.C1OC1.CC1OC1
EPA Substance Registry System	Propylene oxide ethylene oxide polymer monobutyl ether (9038-95-3)

Safety Data

Hazard Codes	Xn,N
Risk Statements	20/21/22-38-41 less more
Safety Statements	26-36/37/39 less more
RIDADR	UN 3082 9/PG 3
WGK Germany	3
RTECS	YP8450000

Hazard Information

Chemical Properties

liquid

Uses

Hydraulic fluids, metal working fluids and lubricants, heat transfer fluids, solder assist fluids, quenchants, lubricants, solvents, plasticizers and foam control agents.

Description

Poly(ethylene glycol-ran-propylene glycol) monobutyl ether is a block copolymer that consists of a hydrophilic poly(ethylene glycol) (PEG) segment and a hydrophobic poly(propylene glycol) (PPO) segment. One of the significant features of PEG-PPO monobutyl ether is its amphiphilic nature. This means that it has both hydrophilic and hydrophobic regions within its structure. This property allows PEG-PPO monobutyl ether to form micelles in aqueous solutions, where the hydrophobic PPO segments aggregate in the core while the hydrophilic PEG segments form the outer shell. The formation of micelles gives PEG-PPO monobutyl ether its surfactant properties. In pharmaceuticals, it is utilized as an excipient in drug formulations to improve solubility, stability, and controlled release of drugs. It can also be employed as a carrier for drug delivery systems, enhancing the bioavailability and targeting of therapeutic agents. Furthermore, PEG-PPO monobutyl ether finds applications in cosmetics as an emulsifier and solubilizer for various formulations. The mechanism of action of PEG-PPO monobutyl ether relies on its ability to self-assemble into micelles in aqueous solutions. When added to a system, the hydrophobic PPO segments aggregate together, forming a core, while the hydrophilic PEG segments create a protective shell around the core. This self-assembly process enables PEG-PPO monobutyl ether to solubilize hydrophobic substances and stabilize emulsions. It can also enhance the penetration and absorption of drugs through biological membranes.

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