Description
L 646462 is an antidopaminergic agent.
Uses
L-646462 is an antagonist of dopamine and 5-HT, with selectivity for the peripheral system (the central/peripheral activity ratio of L-646462 is 143). L-646462 can be used in research related to nausea, vomiting, and associated neurological disorders[1].
References
[1] Williams M, et al. L-646,462, a cyproheptadine-related antagonist of dopamine and serotonin with selectivity for peripheral systems[J]. Journal of Pharmacology and Experimental Therapeutics, 1984, 229(3): 775-781. PMID:6547178
