ChemicalBook CAS DataBase List 89-63-4

89-63-4

Name	4-Chloro-2-nitroaniline
CAS	89-63-4
EINECS(EC#)	201-925-4
Molecular Formula	C6H5ClN2O2
MDL Number	MFCD00007836
Molecular Weight	172.57
MOL File	89-63-4.mol

Synonyms

1-AMINO-4-CHLORO-2-NITROBENZENE 2-AMINO-5-CHLORONITROBENZENE 2-NITRO-4-CHLOROANILINE 4-CHLORO-2-NITROANILINE 4-Chloro-2-nitrobenzenamine c.i. azoic diazo component no. 9 FAST RED 3GL BASE O-NITRO-P-CHLOROANILINE PARA CHLORO ORTHO NITRO ANILINE p-Chloro-o-nitroaniline PCONA RED 3G BASE RED 3GL BASE 4-chloro-2-nitro-anilin 4-chloro-2-nitro-benzenamid 4-chloro-2-nitro-benzenamin 4-Chloro-2-nitro-phenylamine Azoene Fast Red 3GL Base Azoene Fast Red 3GL Salt azoenefastred3glbase

Chemical Properties

Appearance	bright orange powder
Melting point	117-119 °C(lit.)
Boiling point	200°C (rough estimate)
density	1.37
refractive index	1.6460 (estimate)
Fp	191 °C
storage temp.	room temp
solubility	0.5g/l (anhydrous substance)
Colour Index	37040
form	Crystalline Powder or Chunks
pka	pK1: 1.10(+1) (25°C)
color	Orange
PH	7 (0.5g/l, H2O, 20℃)
Stability:	Stable. Combustible. Incompatible with strong oxidizing agents.
Water Solubility	INSOLUBLE
BRN	512436
Henry's Law Constant	8.2×10¹ mol/(m³Pa) at 25℃, HSDB (2015)
InChI	1S/C6H5ClN2O2/c7-4-1-2-5(8)6(3-4)9(10)11/h1-3H,8H2
InChIKey	PBGKNXWGYQPUJK-UHFFFAOYSA-N
SMILES	Nc1ccc(Cl)cc1[N+]([O-])=O
CAS DataBase Reference	89-63-4(CAS DataBase Reference)
NIST Chemistry Reference	Aniline, 4-chloro-2-nitro-(89-63-4)
EPA Substance Registry System	89-63-4(EPA Substance)

Safety Data

Symbol(GHS)	GHS06,GHS08,GHS09
Signal word	Danger
Hazard statements	H300+H310+H330-H373-H410
Precautionary statements	P262-P273-P280-P302+P352+P310-P304+P340+P310-P314
Hazard Codes	T+,N,T
Risk Statements	R26/27/28:Very Toxic by inhalation, in contact with skin and if swallowed . R33:Danger of cumulative effects. R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment . less more
Safety Statements	S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) . S36/37:Wear suitable protective clothing and gloves . S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . S61:Avoid release to the environment. Refer to special instructions safety data sheet . less more
RIDADR	UN 2237 6.1/PG 3
WGK Germany	2
RTECS	BX1575000
Autoignition Temperature	964 °F
Hazard Note	Very Toxic
TSCA	Yes
REACH Registrations	Active
HazardClass	6.1
PackingGroup	III
HS Code	29214210
Storage Class	6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials
Hazard Classifications	Acute Tox. 1 Dermal Acute Tox. 2 Inhalation Acute Tox. 2 Oral Aquatic Acute 1 Aquatic Chronic 2 STOT RE 2
Hazardous Substances Data	89-63-4(Hazardous Substances Data)

Raw materials And Preparation Products

Hazard Information

General Description

Bright orange powder.

Reactivity Profile

4-CHLORO-2-NITROANILINE(89-63-4) forms explosive products on reaction with nitric acid. Can react with oxidizing agents.

Air & Water Reactions

Insoluble in water.

Hazard

Toxic by ingestion and inhalation.

Fire Hazard

This compound is probably combustible.

Chemical Properties

bright orange powder

Uses

4-Chloro-2-nitroaniline is used as pharmaceutical intermediate.

Uses

4-Chloro-2-nitroaniline is used almost exclusively as an intermediate in the synthesis of pigments. The greatest potential for human exposure to 4-chloro-2- nitroaniline is in production and use of pigments made from the compound.

Uses

A nitro-aromatic amine with mutagenicity and carcinogenicity

Preparation

4-Chloro-2-nitrobenzenamine of chlorine.

Production Methods

1,4-Dichloro-2-nitrobenzene is aminated at 165 ℃ by using a process similar to that described for 2- nitroaniline.

Purification Methods

Crystallise the aniline from hot H2O (m 115.8-116o), EtOH, EtOH/H2O or *C6H6, and dry it for 10hours at 60o in vacuo. It has m 115.5-116o after sublimation. [Beilstein 12 H 729, 12 I 355, 12 II 396, 12 III 1649, 12 IV 1669.]

Material Safety Data Sheet(MSDS)

Spectrum Detail

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