876170-44-4

Name	3,6-Diazabicyclo[3.2.0]heptane, 3-(5,6-dichloro-3-pyridinyl)-, (1S,5S)-, Monobenzenesulfonate
CAS	876170-44-4
Molecular Formula	C16H17Cl2N3O3S
MDL Number	MFCD28016491
Molecular Weight	402.29
MOL File	876170-44-4.mol

Synonyms

Sofinicline benzenesulfonate 3,6-Diazabicyclo[3.2.0]heptane, 3-(5,6-dichloro-3-pyridinyl)-, (1S,5S)-, Monobenzenesulfonate

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Hazard Information

Uses

Sofinicline benzenesulfonate (ABT 894 benzenesulfonate) is a novel nicotinic acetylcholine receptor agonist, specifically acting on the α4β2 subtype of nAChR (IC50=0.1 nM). Sofinicline benzenesulfonate has the potential to improve cognitive function, including attention, memory and working memory. Sofinicline benzenesulfonate can be used in studies of attention deficit, hyperactivity disorder (ADHD)[1].

References

[1] Fleisher C, et al. Sofinicline: a novel nicotinic acetylcholine receptor agonist in the treatment of attention-deficit/hyperactivity disorder[J]. Expert opinion on investigational drugs, 2014, 23(8): 1157-1163. DOI:10.1517/13543784.2014.934806

Supplier

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Beijing Yisiyan Technology Research Center

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