87414-44-6

Butyrolactone II is a butenolide fungal metabolite that has been found in A. terreus. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) and ABTS free radicals (EC₅₀s = 11.5 and 68.5 μM, respectively). It inhibits 5-lipoxygenase (5-LO; IC₅₀ = 21.43 μg/ml) and α-glucosidase (IC₅₀ = 0.126 mM).

Butyrolactone II is an antibiotic, a 5-LOX inhibitor and has shown DPPH radical-scavening activity.

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