AO-1535 is a semisynthetic monoglycosylceramide derived from O-glycosilated sphingosine. It has been shown to inhibit superoxide production by macrophages suggesting a potential clinical application of AO 1535 in the treatment of inflammatory dermatoses.
Uses
AO-1535 is a semisynthetic monoglycosylceramide that inhibits the production of reactive oxygen intermediates in human monocytes and macrophages stimulated by phorbol ester and chemotactic tetrapeptide. AO-1535 can be used for the research of inflammatory dermatoses[1].
References
[1] Spampinato G, et al. AO 1535 inhibits O2- production by human macrophages. Immunopharmacology. 1992 Jul-Aug;24(1):25-30. DOI:10.1016/0162-3109(92)90066-l
