869743-37-3

Nivitol is a miscellaneous reagent used in synthesis of a novel tyrosinase inhibitor which acts as a melanin inhibitor.

Researchers assessed the in vitro antitumor activity of UP302 in different tumor cells. It inhibited the growth of certain cancer cell lines and especially in leukemia cells^[1].

4-[3-(2,4-Dimethoxy-3-methylphenyl)propyl]-1,3-benzenediol (UP302) can be found in the medicinal plant Dianella ensifolia.

[1] Wei, J., Zhong, X., Peng, H., Cui, B., Yue, X., Sun, Z., & Shi, J. (2024). Dimethoxytolyl propylresorcinol induces apoptosis and mitophagy in human leukemia cells through the PI3K/AKT pathway. Journal of Cancer, 15 1, 103–112. https://doi.org/10.7150/jca.89243