86293-41-6

The empirical formula for this alkaloid should read C21H24N203 and the structure is that given above. This alkaloid has been fully described by Malikov and his colleagues. It forms colourless crystals with m.p. 222-3°C from MeOH and has the following specific rotations: [α]_D- 57.3° (c 2.01, MeOH) and [α] _D - 83.5° (c 0.3, pyridine). Among the crystalline salts and derivatives that have been prepared are the hydrochloride, m.p. 265-8°C; hydrobromide, m.p. 285-6°C; hydriodide, m.p. 255-8°C and the methiodide, m.p. 258-260°C.

ChEBI: An indole alkaloid that is canthin-6-one substituted by a hydroxy group at position 10. Isolated from Simaba multiflora, it exhibits antineoplastic activity.

Malikov, Yadishev, Yunusov, Khim. Prir. Soedin., 2, 338 (1966)