86048-40-0

Name	Quazolast
CAS	86048-40-0
Molecular Formula	C12H7ClN2O3
MDL Number	MFCD00864797
Molecular Weight	262.65
MOL File	86048-40-0.mol

Synonyms

RHC3988 RHC-3988 RHC 3988 Quazolast methyl 5-chlorooxazolo[4,5-h]quinoline-2-carboxylate 5-Chlorooxazolo[4,5-h]quinoline-2-carboxylic acid methyl ester Oxazolo[4,5-h]quinoline-2-carboxylic acid, 5-chloro-, methyl ester

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Hazard Information

Uses

Anti-asthmatic; inhibitor (mediator release).

Definition

ChEBI: Quazolast is a member of quinolines and an organochlorine compound.

in vivo

Quazolast (0.2, 1, 5 mg/kg; p.o.) reduces the gastric damage in rats induced by absolute ethanol (0.9 mg/kg)^[1].
Quazolast (3.1, 6.3, 12.5, 25 mg/kg; p.o.) reduces the gastric damage associated with 0.6 N HC1 administration^[1].

Animal Model:	150 g Male Sprague Dawley rat^[1]
Dosage:	0.2, 1, 5 mg/kg
Administration:	P.o.
Result:	Decreased the rat gastric mucosa damage in a dose dependent manner and reduced the gastric ulcer index (68%) at 5 mg/kg in rat induced by absolute ethanol (0.9 mg/kg).

Supplier

Hangzhou ChangCun Biotechnology Co., Ltd.

Telephone0571-; 13567100326

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList19101/0_EN.htm

Shanghai Yifei Biotechnology Co. , Ltd.

Telephone021-65675885 18964387627

Websitehttp://www.efebio.com

TargetMol Chemicals Inc.

Telephone 15002134094

Websitehttps://www.targetmol.cn/

Shanghai Amole Biotechnology Co., Ltd.

Telephone13370042665 18916960931

Websitehttps://www.amole.com.cn/

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