858345-57-0

Salvinorin A carbamate is a potent κ-opioid receptor (KOR) full agonist that is almost as potent as salvinorin A with EC₅₀ values of 6.2 and 4.5 nM, respectively, for activation of the human KOR to enhance binding of [³⁵S]GTPγS. The addition of a carbamate group to salvinorin A increases biological stability by decreasing deacetylation.