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Hepoxilin A3, is nonclassic eicosanoid hormones involved in inflammation. They are appear to be pro-inflammatory in the skin, but hey are anti-inflammatory agents in human neutrophils. Hepoxilin A3, are potent insulin secretagogues. Hepoxilins are also produced in the brain, under oxidative stress.

ChEBI: A C20 trienoic hydroxy fatty acid consisting of 8-hydroxyicosa-5,9,14-trienoic acid having an epoxy group at the 11,12-position.