851202-49-8

Lu AA41063 is a potent and selective hA2A receptor antagonist.

Lu AA41063 is an adenosine A2A receptor antagonist that may be useful in the treatment of Parkinson's disease. Lu AA41063 has a Ki value of 5.9 nM and targets the human A2A receptor.

[1] Selective degradation of polo‐like kinase 1 by a hydrophobically tagged inhibitor of the Polo‐box domain
[2] Discovery of novel polo-like kinase 1 polo-box domain inhibitors to induce mitotic arrest in tumor cells