ChemicalBook CAS DataBase List 848133-17-5

848133-17-5

Name	HKI 357
CAS	848133-17-5
Molecular Formula	C31H29ClFN5O3
MDL Number	MFCD26792555
Molecular Weight	574.05
MOL File	848133-17-5.mol

Chemical Properties

Boiling point	747.6±60.0 °C(Predicted)
density	1.34±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Soluble to 100 mM in DMSO and to 25 mM in ethanol
form	Powder
pka	12.37±0.43(Predicted)
color	Off-white to yellow

Hazard Information

Spectrum Detail

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Shanghai Lollane Biological Technology Co.,Ltd.

Telephone021-52996696，15000506266 15000506266

Websitehttp://www.bioll.com

Amadis Chemical Company Limited

Telephone571-89925085

Websitehttp://www.amadischem.com

DC Chemicals

Telephone021-58447131 13564518121

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList927327/0.htm

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Telephone 18818260767

Websitehttp://www.chemegen.com

ShangHai ChuanQian Chemcial Technique Centre

Telephone 15869524721

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList68594/0.htm

MedBioPharmaceutical Technology Inc

Telephone021-69568360 18916172912

Websitehttp://www.med-bio.cn/

cjbscvictory

Telephone13348960310 13348960310

Websitehttp://www.weikeqi-biotech.com/

Beijing Jin Ming Biotechnology Co., Ltd.

Telephone010-60605840 15801484223;

Websitehttp://www.jm-bio.com/

Bide Pharmatech Ltd.

Telephone400-1647117 13681763483

Websitehttps://www.bidepharm.com/

TargetMol Chemicals Inc.

Telephone 4008200310

Websitehttps://www.targetmol.cn/

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Telephone025-66113011 18112977050

Websitehttp://www.aikonchem.com

Nanjing Shizhou Biology Technology Co.,Ltd

Telephone025-85560043 15850508050

Websitehttp://www.synzest.com

Shanghai Aladdin Biochemical Technology Co.,Ltd.

Telephone +86-18521732826

Websitehttp://www.aladdin-e.com/

RD International Technology Co., Limited

Telephone 18024082417

Websitehttps://www.ruidiresearch.com

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Cell Line:	NCI-H1975 bronchoalveolar cell line
Concentration:	0.01, 0.01, 0.1, 1 and 10 μM
Incubation Time:
Result:	Suppressed ligand-induced EGFR autophosphorylation and its downstream signaling AKT and MAPK phosphorylation.

848133-17-5

Chemical Properties

Hazard Information

Biological Activity

in vitro

target

Spectrum Detail

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