ChemicalBook CAS DataBase List 848133-17-5

848133-17-5

Name	HKI 357
CAS	848133-17-5
Molecular Formula	C31H29ClFN5O3
MDL Number	MFCD26792555
Molecular Weight	574.05
MOL File	848133-17-5.mol

Chemical Properties

Boiling point	747.6±60.0 °C(Predicted)
density	1.34±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Soluble to 100 mM in DMSO and to 25 mM in ethanol
form	Powder
pka	12.37±0.43(Predicted)
color	Off-white to yellow

Hazard Information

Spectrum Detail

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Shanghai Lollane Biological Technology Co.,Ltd.

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Shanghai Chaolan Chemical Technology Center

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Amadis Chemical Company Limited

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DC Chemicals

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ShangHai ChuanQian Chemcial Technique Centre

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MedBioPharmaceutical Technology Inc

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cjbscvictory

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Beijing Jin Ming Biotechnology Co., Ltd.

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Bide Pharmatech Ltd.

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TargetMol Chemicals Inc.

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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

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Nanjing Shizhou Biology Technology Co.,Ltd

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Shanghai Aladdin Biochemical Technology Co.,Ltd.

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RD International Technology Co., Limited

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Elucigen bio

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Cell Line:	NCI-H1975 bronchoalveolar cell line
Concentration:	0.01, 0.01, 0.1, 1 and 10 μM
Incubation Time:
Result:	Suppressed ligand-induced EGFR autophosphorylation and its downstream signaling AKT and MAPK phosphorylation.

848133-17-5

Chemical Properties

Hazard Information

Biological Activity

in vitro

target

Spectrum Detail

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