ChemicalBook CAS DataBase List 845264-92-8

845264-92-8

Name	Atacicept
CAS	845264-92-8

Chemical Properties

form	Liquid
color	Colorless to light yellow

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Animal Model:	Male DBA/1 mice with CIA models^[1]
Dosage:	100 μg
Administration:	intraperitoneal injection; three times of week for 21 days
Result:	Increased serum titers of anti-collagen Abs and few overt signs of disease.

Animal Model:	BALB/c mice^[1]
Dosage:	100 μg
Administration:	intraperitoneal injection; three times of week for 14 days
Result:	Reduced mature B cell populations but had little effect on other cell lineages. Blocked the development of B cells at the transition from T1 to T2 and the development of MZ B cells in the spleen. Decerased the serum levels of IgM about 2.3-fold.