82989-25-1

Tazanolast is an orally active antiallergic agent useful in the treatment of bronchial asthma and nasal allergy. Mechanistically it appears to inhibit IgG and IgE-mediated antigen-antibody reactions.

White or yellowish-white crystals or crystalline powder with a slightly bitter odor. Freely soluble in acetone, moderately soluble in methanol, ethanol, or acetonitrile, poorly soluble in ether, and practically insoluble in water. Acute toxicity LD50 for male and female mice, male and female rats (mg/kg): >4000, >4000, >4000, >4000, >4000 oral; >4000, >4000, >4000, >4000 subcutaneous; 1145, 1191, 1423, 1528 intraperitoneal; 1126, 1121, 1119, 1277 intravenous.

Wakamoto (Japan)

TAZANOLAST is used for bronchial asthma.

ChEBI: Tazanolast is an organic molecular entity.

Tazalest; Tazanol