Coelogin is an orally active osteoprotective agent which activates the ER-Erk and Akt-dependent signaling pathways that stimulate the osteoblastogenesis in osteoblast cells. Coelogin can be utilized in osteoporosis research[1].
Definition
ChEBI:Coelogin is a member of phenanthrenes.
References
[1] Prakash R, et al. Phenanthrenoid Coelogin Isolated from Coelogyne cristata Exerts Osteoprotective Effect Through MAPK-Mitogen-Activated Protein Kinase Signaling Pathway. Calcif Tissue Int. 2021 Jul;109(1):32-43. DOI:10.1007/s00223-021-00818-3
