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Benzotriazole amino acids, or aminoacylbenzotriazolides, are versatile reagents for synthesizing peptides as well as their mimetics and conjugates. Benzotriazole amino acids have been used for the preparation of diverse derivatives including:

• Polypeptidal benzotriazolides
• Peptidomimetics, such as aminoxypeptides, depsipeptides and heterocyclic peptidomimetics
• Tagged peptides and peptidomimetics, particularly those with fluorescent labels,
• N, O, S, and C linked peptide conjugates

reaction type: solution phase peptide synthesis