81024-42-2

Light Beige Low Melting Solid

(S)-Enantiomer of Metoprolol. Antihypertensive; antianginal; antiarrhythmic (class II)

(S)-Enantiomer of Metoprolol. Antihypertensive; antianginal; antiarrhythmic (class II).

Clinical experience with chirally pure (S)-(-)-metoprolol at half the dose of racemate has shown it to be as effective as racemate in the treatment of patients with hypertension and angina. S-metoprolol has been shown to be effective and well-tolerated in patients with coexisting diabetes, COPD, and hyperlipidaemia. This confirms higher cardioselectivity of S-metoprolol in clinical settings.^[1]

[1] Dasbiswas, A., Shinde, S., & Dasbiswas, D. (2008). S-metoprolol: the 2008 clinical review. Journal of the Indian Medical Association, 106 4, 259–262. https://pubmed.ncbi.nlm.nih.gov/18828349/