80394-72-5

Oxanosine is an antibiotic isolated from the streptomyces MG265-CF34, which has anti-tumor activity. Oxanosine is also a substrate for adenosine deaminase[1][2].

-20°C

[1] Runhan Yu, et al. Oxanosine monophosphate is a covalent inhibitor of inosine 5’-monophosphate dehydrogenase. Chem Res Toxicol. 2019 Feb 25;32(3):456–466.
[2] Papiya Majumdar, et al. Oxanosine is a substrate of adenosine deaminase. Implications for the quest for a toxicological marker for nitrosation activity. Chem Res Toxicol. 2005 Dec;18(12):1830-41. DOI:10.1021/tx050232h