802918-36-1
Name | Cinacalcet IMpurity 9 |
CAS | 802918-36-1 |
Molecular Formula | C22H24F3N |
Molecular Weight | 359.44 |
MOL File | 802918-36-1.mol |
Synonyms
Cinacalcet-13
Cinacalcet IMpurity 9
CicalcetDihydroImpurity2HCl
Cinacalcet Dihydro Impurity 2 HCl
(R)-N-(1-(5,6-dihydronaphthalen-1-yl)ethyl)-
N-[(1R)-1-(5,6-dihydronaphthalen-1-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine
(αR)-5,6-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine
1-Naphthalenemethanamine, 5,6-dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-, (αR)-
N-(1-(7,8-dihydrophthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-aminehydrochloride
Cinacalcet impurity 13/Cinacalcet Dihydro Impurity 2 HCl/(R)-N-(1-(5,6-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl) phenyl)propan-1-amine hydrochloride
Hazard Information
Uses
(αR)-5,6-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine is synthetically prepared though a double bond migration in Heck reaction during the preparation of cinacalcet congeners. This enantiomerically pure material is seperated from its counter part, (αR)-7,8-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine (D455330) using HPLC.
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