799268-73-8

Name	(S)-phosphoric acid Mono-[3-(4-benzyloxy-phenyl)-2-octadec-9-enoylaMino-propyl] ester (aMMoniuM salt)
CAS	799268-73-8
Molecular Formula	C34H55N2O6P
MDL Number	MFCD22416852
Molecular Weight	618.8
MOL File	799268-73-8.mol

Synonyms

VPC 12249 (S) (S)-phosphoric acid Mono-[3-(4-benzyloxy-phenyl)-2-octadec-9-enoylaMino-propyl] ester (aMMoniuM salt) (S)-PHOSPHORIC ACID MONO-[3-(4-BENZYLOXY-PHENYL)-2-OCTADEC-9-ENOYLAMINO-PROPYL] ESTER (AMMONIUM SALT);VPC 12249 (S)

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Chemical Properties

storage temp.

-20°C

Hazard Information

Uses

VPC 12249 has been used as lysophosphatidic acid (LPA)_1/3receptor antagonist in various experimental studies.

General Description

VPC 12249 is an N-acyl (oleoyl) serine phosphate-based compound.

Biochem/physiol Actions

Lysophosphatidic acids (LPAs) are bioactive lipid mediators. It interacts with at least six specific LPA receptors (LPA1-6) to mediate extracellular signaling pathway. LPA and its receptors (LPA1-3) are implicated in the pathogenesis of radiation pneumonitis (RP). VPC 12249 (S) inhibits the binding ofLPA to LPA1 and LPA3 receptor.

Supplier

Sigma-Aldrich

Telephone021-61415566 800-8193336

Websitehttps://www.sigmaaldrich.cn

Codow Chemical Co.,Ltd.

Telephone 18620099427

Websitehttp://www.howeipharm.com

Shanghai EFE Biological Technology Co., Ltd.

Telephone021-65675885 18964387627

Websitehttp://www.efebio.com

Chengdu Dianchun Technology Co., Ltd

Telephone400-1166-196 18502815961

Websitehttp://www.hx-r.com

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