78095-19-9

(R)-(+)-8-Hydroxy-DPAT hydrobromide has been used as a 5-HT1A agonist:

• in mice to test the activity of the serotonin receptor
• to test its effect on zebrafish melanocyte migration and survival
• to stimulate hippocampal neurons

(R)-(+)-8-Hydroxy-DPAT administration reduces aggressive behavior. It decreases food intake by modifying the sensitivity of 5-HT1A receptor during food deprivation.

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