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Biotin-aniline is a probe with substantially high reactivity towards RNA and DNA. Biotin-aniline is also a novel APEX2 substrate. Biotin-aniline can label proteins via miniSOG. Biotin-aniline emerges as more efficient probe for capturing subcellular transcriptome in living cells with high spatial specificity[1][2].

Biotin-aniline is a probe with substantially high reactivity towards RNA and DNA. Biotin-aniline emerges as more efficient probe for capturing subcellular transcriptome in living cells with high spatial specificity[1].

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[1]. Zhou Y, et al. Expanding APEX2 Substrates for Proximity-Dependent Labeling of Nucleic Acids and Proteins in Living Cells. Angew Chem Int Ed Engl. 2019;58(34):11763-11767.