76265-48-0

Nodusmicin is a macrolide antibiotic. It has activity against antibiotic-susceptible and -resistant S. aureus with MIC values of 125, 250, and 250 μg/ml for UC-76, UC-6685, and UC-6690 strains, respectively.

Nodusmicin is a co-metabolite of nargenicin, bearing the core macrocyclic lactone but lacking the pyrrole ester. Like nargenicin, nodusmicin is a potent antibiotic active against both aerobic and anaerobic bacteria. Lack of availability has restricted a more extensive investigation of nodusmicin.

Nodusmicin is a potent antibiotic against aerobic and anaerobic bacteria.