75921-88-9

[DAla2, DArg6] Dynorphin A, (1-13) (porcine) (DADAD) is an opioid peptide (dynorphinl-13, DYN) derivative found in porcine pituitary extracts. DYN is highly potent at the peripheral opioid receptors GPI and MVD, but is readily and rapidly degraded in vivo. [DAla2, DArg6] Dynorphin A, (1-13) (porcine) has some resistance to enzymatic cleavage and prevents peptide cleavage by enzymes[1].

[1] Wüster M, et al. Opiate activity and receptor selectivity of dynorphin1-13 and related peptides. Neurosci Lett. 1980 Oct 20;20(1):79-83. DOI:10.1016/0304-3940(80)90237-2