7417-67-6

N-methyl-N-nitrosoacetamide is an alkylating agent; a source of diazomethane; can be used as an activated acylating agent and as a precursor to esters and olefins.

Nitrosation of N-alkyl amides with Sodium Nitrite/acid mixtures, Nitrosyl Chloride, or Nitrogen Dioxide. N-Deprotonation of the amide with n-Butyllithium or Sodium Hydride, followed by treatment with nitrosonium salts or Nitrogen Dioxide, is a second approach that is particularly useful in the preparation of thermally labile nitrosoamides.