73815-11-9

Name	cimoxatone
CAS	73815-11-9
EINECS(EC#)	277-613-7
Molecular Formula	C19H18N2O4
MDL Number	MFCD00867655
Molecular Weight	338.36
MOL File	73815-11-9.mol

Synonyms

MD-780515 cimoxatone 3-[[4-[5-(Methoxymethyl)-2-oxooxazolidin-3-yl]phenoxy]methyl]benzonitrile Benzonitrile, 3-[[4-[5-(methoxymethyl)-2-oxo-3-oxazolidinyl]phenoxy]methyl]- 3-[[4-[5-(methoxymethyl)-2-oxo-1,3-oxazolidin-3-yl]phenoxy]methyl]benzonitrile

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Chemical Properties

Boiling point	474.51°C (rough estimate)
density	1.2855 (rough estimate)
refractive index	1.6140 (estimate)
pka	0.25±0.40(Predicted)

Hazard Information

Uses

Cimoxatone is a monoamine oxidase form A (MAO-A) selective inhibitor which shows adverse effects in combination with Tyramine.

in vivo

Cimoxatone (20 mg/kg; p.o.) enhances the anorectic action of 5-HT (1 mg/kg; s.c.) in rats^[1].

Animal Model:	250-300 g, Adult male Wistar rats^[1]
Dosage:	20 mg/kg
Administration:	P.o.
Result:	Significiantly reduced sucrose intake induced by 1 mg/kg 5-HT or its vehicle injected 2 and 24 h later, significantly enhanced the anorectic action of 5-HT at 2 h but not at 24 h.

IC 50

MAO-A

Supplier

Changzhou Xuanye Technology Co., Ltd

Telephone 15195022192;

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList152306/0_EN.htm

Shaanxi Dideu Medichem Co. Ltd

Telephone+86-029-81138252 +86-173 9270 1263

Websitehttps://www.chemicalbook.com/manufacturer/shaanxi-dideu-medichem-222/

TargetMol Chemicals Inc.

Telephone 15002134094

Websitehttps://www.targetmol.cn/

Shaanxi Dideu Medichem Co. Ltd

Telephone81148925 17391631969

Website

Zibo Hangyu Biotechnology Development Co., Ltd

Telephone+86-0533-2185556 +86-15965530500

Websitehttps://www.chemicalbook.com/manufacturer/hangyu-chemical-25178/

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