Chemical Properties
Crystalline Solid
Uses
Phenobarbital-d5, is the labeled analogue of Phenobarbital (P316760), which is Anticonvulsant, sedative, and hypnotic.
controlled substance (depressant)
Uses
This is a controlled substance (depressant). Anticonvulsant; sedative; hypnotic
Description
Phenobarbital-d5 (ethyl-d5) is an analytical reference material intended for use as an internal standard for the quantification of phenobarbital by GC- or LC-MS. Phenobarbital is characterized as a barbiturate. Phenobarbital-d5 (ethyl-d5) is regulated as a Schedule IV compound in the United States. This product is intended for research and forensic applications.
Definition
ChEBI: Phenobarbital-d5 is a pyrimidone and a deuterated compound.
Synthesis
Phenobarbital-D5 was prepared as follows: 1.0 g (0.0166 mol) of urea and 1.0 g (0.0416 mol) of sodium hydride were added to a 50 ml round bottom flask equipped with a stir bar, a reflux condenser and a rubber septum under nitrogen. While stirring, 3.4 g (
References
[1] LEONARD L JOHNSON Uttam G. Quantitation of amobarbital, butalbital, pentobarbital, phenobarbital, and secobarbital in urine, serum, and plasma using gas chromatography-mass spectrometry (GC-MS).[J]. Methods in molecular biology, 2010, 603: 65-74. DOI:
10.1007/978-1-60761-459-3_7
