69579-74-4

Adustin, an antifungal antibiotic, is a polypeptide with translation-inhibiting activity. Adustin inhibits translation in a cell-free rabbit reticulocyte lysate system with an IC50 of 0.34 μM[1][2].

[1] Ng TB, et al. Adustin, a small translation-inhibiting polypeptide from fruiting bodies of the wild mushroom Polyporus adusta. Peptides. 2004 Apr;25(4):689-92. DOI:10.1016/j.peptides.2004.01.021
[2] Z. Guan-Ping, et al. Adustin, a new antifungal antibiotic 1. Production, isolation and properties of adustin. Acta Microbiologica Sinica, 1978, Vol. 18, No. 4, 317-319 ref. 2.