68000-92-0

Farnesylcysteine (FC) is a competitive inhibitor of ICMT. The fcly mutant has quantitatively low farnesylcysteine (FC) lyase activity and an enhanced response to ABA. Farnesylcysteine induces an ABA hypersensitive phenotype in Arabidopsis thaliana[1].

ChEBI: An S-farnesyl-L-cysteine where the C2C double bonds at the 2- and 6-positions both have (E)-configuration.

[1] Huizinga DH et al. Farnesylcysteine lyase is involved in negative regulation of abscisic acid signaling in Arabidopsis. Mol Plant. 2010 Jan;3(1):143-55. DOI:10.1093/mp/ssp091