Caftaric acid is a phenolic acid and a tartaric acid ester form of caffeic acid (Item No.
70602).
1 It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No.
14805) free radicals in a cell-free assay (EC
50 = 20.4 μM) and inhibits oxidation of LDL isolated from human plasma by 97.6% compared to vehicle control
in vitro when used at a concentration of 5 μM.
2,3 Caftaric acid is the main phenolic compound in
V. vinifera white, pink, and black table grapes as well as various wines.
4 In vivo, caftaric acid content in dietary-administered red wine positively correlates with inhibition of protein carbonylation and decreased superoxide dismutase (SOD), glutathione peroxidase (Gpx), and catalase activities in mice.
5 
