67731-19-5

Name	N-[5-Hydroxy-5-(hydroxymethyl)-3-imino-2-methoxy-1-cyclohexen-1-yl]glycine
CAS	67731-19-5
Molecular Formula	C10H16N2O5
Molecular Weight	244.24
MOL File	67731-19-5.mol

Synonyms

Palythine (5-hydroxy-5-(hydroxymethyl)-3-imino-2-methoxycyclohex-1-en-1-yl)glycine N-[5-Hydroxy-5-(hydroxymethyl)-3-imino-2-methoxy-1-cyclohexen-1-yl]glycine Glycine, N-[(5S)-5-hydroxy-5-(hydroxymethyl)-3-imino-2-methoxy-1-cyclohexen-1-yl]-

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Chemical Properties

Boiling point	530.3±50.0 °C(Predicted)
density	1.46±0.1 g/cm3(Predicted)
pka	4.14±0.10(Predicted)

Hazard Information

Uses

Palythine is a photoprotective and antioxidant agent. Palythine exhibits photoprotective and antioxidant activities by absorbing ultraviolet radiation (UVR) energy and dissipating it as heat, as well as through antioxidant mechanisms such as direct chemical quenching and Nrf2 pathway activation, reducing cell death, DNA damage, inflammation, and oxidative stress. Palythine is promising for research of skin-related diseases such as skin cancer, photoaging, and photosensitivity disorders[1].

Definition

ChEBI: Palythine is an organonitrogen compound and an organooxygen compound. It is functionally related to an alpha-amino acid.

References

[1] Lawrence KP, et al. Molecular photoprotection of human keratinocytes in vitro by the naturally occurring mycosporine-like amino acid palythine. Br J Dermatol. 2018 Jun;178(6):1353-1363. DOI:10.1111/bjd.16125

Supplier

ShangHai Caerulum Pharma Discovery Co., Ltd.

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Websitehttp://www.caerulumpharma.com

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