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2'-Deoxy-NAD+ is a noncompetitive inhibitor for NAD+ with a Ki of 32 μM. 2'-Deoxy-NAD+ can be utilized as a substrate to study the ADP-ribosyl transfer reaction[1].

[1] Alvarez-Gonzalez R, et al. In Vitro ADP-Ribosylation Utilizing 2′ Deoxy-NAD+ as a Substrate[J]. ADP-Ribose Transfer Reactions: Mechanisms and Biological Significance, 1989: 53-56.