Saframycin A has the effect of anti-Gram-positive bacteria. Saframycin A also has weak activity against Gram-negative bacteria and mycobacteria. Saframycin A has the effect of inhibiting mouse lymphocyte L-1210 with an ID50 of 0.0056 μM[1].
References
[1] Ryo Tanifuji, et al. Chemo-enzymatic Total Syntheses of Jorunnamycin A, Saframycin A, and N-Fmoc Saframycin Y3. J Am Chem Soc. 2018 Aug 29;140(34):10705-10709.
