Description
A 924 is an antineoplastic amino acid derivative.
Uses
A 924 is an amino acid derivative-based, orally active antitumor agent. A 924 is effective in inhibiting ascites tumors in rat models by intraperitoneal injection or oral administration. The LD50 of A 924 in mice is >1.5 g/kg and >4.5 g/kg by intraperitoneal injection or oral administration, respectively. A 924 does not cause teratogenicity or adverse reactions in normal or pregnant mice[1].
References
[1] Fujita H, et al. A new antineoplastic amino acid derivative, A-924. Cancer Treat Rep. 1977 Nov;61(8):1577-8. PMID:200358
