64204-55-3

Esaprazole (50-450 mg/kg; intraduodenal administration; single dose) can inhibit the secretion of gastric acid and pepsin in a dose-dependent manner in Wistar rats. Moreover, Esaprazole (25, 50, and 100 mg/kg; intraperitoneal injection; single dose) can also inhibit the hypersecretion of acid induced by Bethanechol (HY-B0406) (500 μg/kg/h) and the acid secretory response induced by vagal stimulation^[1].