637774-61-9

Name	SR13668
CAS	637774-61-9
Molecular Formula	C25H22N2O5
MDL Number	MFCD25976855
Molecular Weight	430.45
MOL File	637774-61-9.mol

Synonyms

SR13668 LS-190469 CHEMBL245030 BMTPVPNVQOYGAP-UHFFFAOYSA-N SR13668; SR 13668; CHEMBL245030; LS-190469 Indolo[2,3-b]carbazole-2,10-dicarboxylic acid, 5,7-dihydro-6-methoxy-, 2,10-diethyl ester

show less show more

Chemical Properties

Boiling point	688.9±50.0 °C(Predicted)
density	1.365±0.06 g/cm3(Predicted)
pka	16.18±0.30(Predicted)

Hazard Information

Uses

SR13668 is a potent indole analog derived from indole-3-carbinol (I3C), known for its natural anticancer properties but limited by poor metabolic characteristics. Developed to enhance I3C's anticancer efficacy, SR13668 effectively inhibits growth factor-stimulated Akt activation. It demonstrates strong oral anticancer activity across different cancer types in preclinical studies, showing promise in clinical development due to its favorable safety profile and potent therapeutic effects[1].

References

[1] Computer-Aided Rational Drug Design: A Novel Agent (SR13668) Designed to Mimic the Unique Anticancer Mechanisms of Dietary Indole-3-Carbinol to Block Akt Signaling

Supplier

NCE Biomedical Co.,Ltd.

Telephone4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList15748/0_EN.htm

SPIRO PHARMA

Telephone

Websitehttp://www.spiropharma.com.cn

Amadis Chemical Company Limited

Telephone571-89925085

Websitehttp://www.amadischem.com

Suzhou Meishi Biotechnology Co., Ltd.

Telephone 1173954148q

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList1822805/0_EN.htm

TargetMol Chemicals Inc.

Telephone 15002134094

Websitehttps://www.targetmol.cn/

Related Products

636-58-8 842148-40-7

146986-50-7 9004-61-9

PROMPT×

PROMPT
The What'sApp is temporarily not supported in mainland China

Cancel

Determine

Send Inquriy