609-39-2

solid

A minor antimicrobial used in veterinary medicine.

ChEBI: 2-nitrofuran is a member of furans and a C-nitro compound.

2-Nitrofuran is a yellow crystalline solid with molecular weight of 113.07152 g mol^-1. The boiling point of 2-nitrofuran is 84 ℃ at 17 hPa and the melting point is 29–33 ℃. It is a flammable solid. Its flash point is 88 ℃ (closed cup). Vapor pressure is 0.398mmHg at 25 ℃. This compound is soluble in H2O and ethanol. Its density is 1.344 g cm^-3.
The partition behavior of 2-nitrofuran in water, sediment, and soil is 0.8. No data are available on its environmental persistency (degradation/speciation), long-range transport, bioaccumulation, and biomagnification. This chemical is stable but it is incompatible with strong oxidizing agents.

2-Nitrofuran reacts with DNA to form complexes, induces interstrand cross-links, produces alkali-labile lesions, and interferes with nucleic acid synthesis. Removal of the nitro group decreases the mutagenic activity.