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  In Japan, potassium 5-nitroorotate monohydrate is mainly used as an ingredient in over-the-counter multivitamin medications and as an additive in soft drinks. In Western Europe, it is not only a component of pharmaceutical vitamins but also widely used in cosmetics as a nutritional cosmetic matrix, which can be absorbed by skin cells, promoting cell metabolism and inhibiting skin aging. In the United States, there is considerable research on potassium 5-nitroorotate monohydrate. A series of orotic acid-based drugs, such as nitroorotate and aminoorotate, have been developed both domestically and internationally. Potassium 5-nitroorotate monohydrate possesses an asymmetric spatial structure and various coordination functional groups, enabling it to form a rich variety of coordination compounds with different metal ions. Potassium 5-nitroorotate monohydrate is a key intermediate in the synthesis of dipyridamole, which is a precursor in the synthesis of persantin and aggrenox.;

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