6045-08-5

Clear Colourless Oil

tert-Butylamine is common reagent in pharmaceuticals syntheses. Used in the preparation of aminoBODIPY compounds for chemical analyses. Also it aids in the synthesis of benzylurea-based insecticides c ontaining amide and sulfonate groups. It has also been used in the synthesis of BPTES analogs, that act as glutaminase inhibitors, which can attenuate the growth of human lymphoma B cells. This is the labeled analog.

In a 100 mL flask with a thermometer and condenser tube, 3.607 g (0.1 mol) of methanol-D4 was added and cooled to 0 C. Under stirring conditions, 38.071 g (0.15 mol) of iodine, and an appropriate amount of red phosphorus were added slowly in batches, and