6036-76-6

L-erythro Sphinganine (d18:0) is a synthetic bioactive sphingolipid and stereoisomer of sphinganine (d18:0) and D-threo sphinganine . It induces autophagy in HCT116 cells when used at a concentration of 12 μM. L-erythro Sphinganine induces cell cycle arrest of 7R4-LCB1 yeast cells. It is metabolized via sphinganine N-acyltransferase and sphinganine kinase in vivo in rat liver. [Matreya, LLC. Catalog No. 1846]

L-erythro-Dihydrosphingosine is an ester product.

ChEBI: Erythro-dihydrosphingosine is an amino alcohol.

Store at -20°C

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[3] W STOFFEL  K B. Stereospecificities in the metabolic reactions of the four isomeric sphinganines (dihydrosphingosines) in rat liver.[J]. Hoppe-Seyler’s Zeitschrift fur physiologische Chemie, 1973, 354 2: 169-181. DOI: 10.1515/bchm2.1973.354.1.169