60066-35-5

Goyazensolide is an inhibitor of NF-κB that can induce apoptosis in cancer cells and exhibits both anti-inflammatory and anticancer activities. Goyazensolide is a sesquiterpene lactone that can be found in the Argentine herb Centratherum punctatum[1][2][3].

[1] Pierre Alexandre dos Santos, et al. Production of an antiproliferative furanoheliangolide by Lychnophora ericoides cell culture. Chem Pharm Bull (Tokyo). 2004 Dec;52(12):1433-5. DOI:10.1248/cpb.52.1433
[2] Susana Amaya, et al. Inhibition of quorum sensing in Pseudomonas aeruginosa by sesquiterpene lactones. Phytomedicine. 2012 Oct 15;19(13):1173-7. DOI:10.1016/j.phymed.2012.07.003
[3] Acu?a UM, et al. Goyazensolide Induces Apoptosis in Cancer Cells in vitro and in vivo. Int J Cancer Res. 2013;9(2):36-53. DOI:10.3923/ijcr.2013.36.53