DNA damage by 4,5-Dioxovaleric Acid in the presence of ferritin was studied. 4,?5-?Dioxovaleric acid (DOVA) was efficiently converted to ALA by the pyridoxamine 5''-?phosphate (PMP) form of the enzyme, thus it is a reaction intermediate.
Definition
ChEBI:4,5-dioxopentanoic acid is a dioxo monocarboxylic acid consisting of a valeric acid core with the two oxo groups at the 4- and 5-positions. It is functionally related to a valeric acid. It is a conjugate acid of a 4,5-dioxopentanoate.
