ChemicalBook CAS DataBase List 59681-32-2

59681-32-2

Name	L-GLUTAMINE-AMIDE-15N
CAS	59681-32-2
Molecular Formula	C5H10N2O3
MDL Number	MFCD00084214
Molecular Weight	147.15
MOL File	59681-32-2.mol

Chemical Properties

Melting point	185 °C (dec.)(lit.)
storage temp.	Room Temperature
solubility	Aqueous Acid (Very Slightly), Water (Slightly)
form	Solid
color	White to Off-White
Optical Rotation	[α]25/D +33.0°, c = 2 in 5 M HCl
InChI	1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1/i7+1
InChIKey	ZDXPYRJPNDTMRX-QQKKVIQDSA-N
SMILES	N[C@@H](CCC([15NH2])=O)C(O)=O
CAS Number Unlabeled	56-85-9

Safety Data

WGK Germany	3
Storage Class	11 - Combustible Solids

Hazard Information

Uses

(L-Glutamine-amide-15N) Labelled Gluamine. L-Glutamine is an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture. L-Glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however, L-glutamine degrades relatively rapidly. Optimal cell performance usually requires supplementation of the media with L-glutamine prior to use.

Uses

Labelled L-Glutamine (G597000). L-Glutamine is an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture. L-Glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however, L-glutamine degrades relatively rapidly. Optimal cell performance usually requires supplementation of the media with L-glutamine prior to use.

General Description

L-Glutamine is a branched chain, non-essential amino acid. It is one of the most abundant amino acid found in central nervous system (CNS), plasma and human skeletal muscle.(2) L- Glutamine is synthesized by transamination of glutamate catalyzed by glutamine synthetase.

Biochem/physiol Actions

L-Glutamine, a source of nitrogen, mainly contributes to the synthesis of proteins, peptides, purine, pyrimidine, nucleotides, nucleic acids and major precursor of neurotransmitter. It acts as a fuel for the proliferation of lymphocytes and macrophages of immune system, for intestinal tissue to maintain gut integrity and for insulin production.(4)(3) L-Glutamine is released by skeletal muscle during stress conditions.

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