Production Methods
Bromfenvinfos was manufactured using the standard industrial chemistry applied to mid 20th century organophosphate insecticides. Production began with synthesis of a 2,4 dichlorophenylvinyl bromide intermediate, which was then reacted with diethyl phosphoric acid chloride or diethyl phosphite in a controlled esterification step to form the final diethyl phosphate ester. After reaction, the crude material was purified, solvents removed, and the technical grade active ingredient isolated for formulation.