568-21-8

forms colourless prisms from EtOH and has [α]¹⁸_D + 285.1 ° (EtOH). It may be characterized as the sulphate, m.p. 120-1 °c (dec.) and also yields a diacetyl derivative, m.p. 80-5°C.

ChEBI: Isothebaine is an aporphine alkaloid. It derives from a hydride of an aporphine.

Klee., Arch. Pharrn., 252,211 (1914)
Callow, Gulland, Haworth., J. Chern. Soc., 1444 (1929)
Kiseler, Konovalova.,J. Gen. Chern., USSR, 18,142 (1948)
Battersby, Brown.J'roc. Chern. Soc., 85 (1964)
Synthesis:
Battersby, Brown, Clements., J. Chern. Soc., 4550 (1965)
Biosyn thesis:
Battersby et al., Chern. Cornrnun., 230 (1965)