Chemical Properties
White Solid
Uses
A labelled metabolite of Vitamin D, a possible anti-inflammatory steroid.
Uses
A labelled metabolite of Vitamin D, a possibly anti-inflammatory steroid.
Uses
A metabolite of Vitamin D, a possibly anti-inflammatory steroid.
Definition
ChEBI:(24R)-24,25-dihydroxycalciol is a seco-cholestane, a hydroxy seco-steroid and a hydroxycalciol. It has a role as a human metabolite.
Brand name
Osteo D (Teva, Israel).
Biological Activity
(24R)-24,25-Dihydroxyvitamin D3 plays an essential role in calcium and phosphorus homeostasis. (24R)-24,25-Dihydroxyvitamin D3 along with 1α,25(OH)2D3 stimulates bone metabolism.''Cholecalciferol is an inactive form of vitamin D3 which undergoes various levels of hydroxylation to form active vitamin D3 analogs. 1α-Hydroxyvitamin D3 (alfacalcidol) is a synthetic analog th at is metabolized to 1,25-dihydroxycholecalciferolthe biologically active form of vitamin D3. Other analogues of cholecalciferol result from different hydroxylations. 24R,25-Dihydroxyvitamin D3 is a catabolite of 25-Dihydroxyvitamin D3 and a putative regulator of developmental bone formation. 24R,25-Dihydroxyvitamin D3 is a substrate for renal 25-hydroxyvitamin D3 1 α-hydroxylase. 24R,25-Dihydroxyvitamin D3 is an endogenous regulator of apo A-I synthesis through a VDR-independent signaling mechanism a
storage
4°C, protect from light, stored under nitrogen,unstable in solution, ready to use.
