55576-49-3

Endoproteinase Asp-N (Asp-N) is a metalloprotease that can specifically cleave the N-terminal side of aspartyl and cysteic acid residues[1].

[1] Ingrosso D, et, al. Specificity of endoproteinase Asp-N (Pseudomonas fragi): cleavage at glutamyl residues in two proteins. Biochem Biophys Res Commun. 1989 Aug 15;162(3):1528-34. DOI:10.1016/0006-291x(89)90848-6
[2] Grillon C, et, al. Involvement of thymosin beta 4 and endoproteinase Asp-N in the biosynthesis of the tetrapeptide AcSerAspLysPro a regulator of the hematopoietic system. FEBS Lett. 1990 Nov 12;274(1-2):30-4. DOI:10.1016/0014-5793(90)81322-f