Description
An oily base obtained from the bark of Cephaelis Ipecacuanha (Brot) A. Rich,
the alkaloid is characterized as the perchlorate which forms crystals of the monohydrate from aqueous EtOH, m.p. 140-2°C or 193-5°C (dry). This salt has
[α]D - 10.9° (c 3.13, EtOH) and gives an ultraviolet spectrum in ethanol with
two absorption maxima at 232 and 283 mJ1. The base contains a formylmethyl
group and yields a crystalline semicarbazone, m.p. 168-9°C. The optically
inactive base has been synthesized and is also a colourless oil, giving a semicarbazone, m.p. 185-6°C.
References
Battersby, Davidson, Harper.,J. Chem. Soc., 1744 (1959)
Battersby, Harper., ibid, 1748 (1959)
Synthesis:
Santay, Toke, Kolonits., J. Org. Chem., 31, 1447 (1966)
